Tadalafil Cialis Manufacturer in China high purity CAS NO.171596-29-5

Product Name：Tadalafil

Synonyms：CIALIS

CAS：171596-29-5

MF：C22H19N3O4

MW：389.4

EINECS：687-782-2

Melting point：298-300°C

alpha：D20 +71.0°

Fp：2℃

storage temp：Hygroscopic, -20 C Freezer, Under Inert Atmosphere

solubility：DMSO: soluble20mg/mL, clear

Hazard Codes：F,Xn

Risk Statements：11-20/21/22-36

Safety Statements：16-36/37

Chemical Properties：White to Off-White Cyrstalline Solid

Indications and uses：

      Cialis (or Tadalafil)  It is used to treat erectile dysfunction and belongs to a second generation of PDE5 inhibitors. Studies show that Cialis works very quickly, taking effect in around 15-20 minutes, and has a prolonged effect that can last for up to 36 hours. T1/2 is 17.5h.

      tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia.

Wuhan Zenuo Biopharmaceutical Technology Co., Ltd. is a global biopharmaceutical and chemical enterprise, mainly engaged in the customized synthesis, large-scale production and sales of pharmaceutical raw materials intermediates, mainstream fine chemicals, rare chemical raw materials. The company is located in the Guanggu Biological Industry Zone in Wuhan, Hubei Province, with a number of senior and middle-level professionals with many years of experience, and also with the first-class domestic colleges and universities. Laboratory in-depth cooperation to ensure that the company is at the forefront of the international level, can provide global customers with high-quality products and the best price, while providing customized synthesis of chemical products from small-scale to mass production, synthetic circuit formulation, process upgrading and transformation ser. At present, stable supply of products are: kojic acid, Dyclonine hydrochloride, hydrocortisone, dexamethasone, betamethasone and other steroid hormone raw materials and intermediates products, long-term normal supply of products.

Why did you choose us

Strict quality control: good raw materials, good quality, Zenuo Biology has always regarded quality as the life of the enterprise. Zenuo Biology has an independent quality control department and long-term cooperation with the third-party detection structure. All products are strictly tested in accordance with Pharmacopoeia and relevant regulations to ensure that the quality is up to standard.

Advantage price service: The company produces and sells one-stop service. The price of the product is very advantageous. At the same time, our experienced technical team constantly improves and innovates, reduces costs and ensures the quality of the product.

Purchasing Agent Service: Professional team can provide you with timely and thoughtful service, good language communication skills and professional chemical technical consultants, can answer customers'professional academic questions. Our goal is to provide qualified products with reasonable prices for global customers, wholeheartedly provide purchasing agent service to customers, help shorten the procurement time and reduce the procurement cost.

Over the years, our products and services have been exported to the United States, Europe, Africa, Southeast Asia, the Middle East and other countries and regions, and have established long-term stable business relations with customers.